These responses are depending up on the intensity of the stimulus, and also depending up on the individual difference.The stimuli are viral, bacterial, chemicals, severe climatic changes and mental shock etc.

     The responses are postsynaptic potential responses due to pre.synaptic stimulation. The stimulus can be exhibit features of short-term and long-term memory. In an acute condition short-term memory process taking place in the neurons. After the acute condition is over, the body will delete the memory from the neurons. That’s why in acute stage there is no recurrence of responses. E.g. Fever Cold. Diarrhoea etc…

     In chronic conditions the responses are stereotyped due to persistent enhancement of the post-synaptic potential response to pre-synaptic stimulation after a brief period of rapidly repeated stimulation of the pre-synaptic neuron. The fact is that the responses are stereotyped does not exclude the possibility of their being modified by experience. Here long-term memory process (miasmatic background) taking place in the neurons. It is much more prolonged can last for years. E.g. Skin diseases, Asthma, Renal Coliculi, peptic ulcer etc…

     Without application of an exact similimum (anti-miasmatic remedy) this chronic miasmatic condition will not go easily. And we cannot select similimum, possible unless we understand the phenomena of the acting and basic miasms behind. For simplification depending on the responses Hahnemann used the terms Acute, psora, pseudo-psora, sycotic and syphilitic miasms. Psora corresponds to deficiency or lack, inhibition and functional disturbances. Sycotics is a miasm of excess, of exuberance of ostentation of flight, syphilis distruction degeneration aggressiveness, pseudo-psora (psora+syphilis: tubercular) emaciation.

A case of psoric miasm :

     Patients aged 55 yrs, professionally an artist. He was born and brought up from Bangalore. Now he is staying in chennai. He was suffering from contact dermatitis. Since 24 yrs, when I attended the case severe allergic reaction of the skin, thick scabs and cracks with oozing. < to sweet, sugar, pollens and < to Bangalore atmosphere. Whenever he attended any exhibitions in Bangalore he was affected by this condition. After giving anti-miasmatic drug sulphur 30, 200, 1m in infrequent doses for 4 months. Now he is perfectly all right, there is no dermatitis condition after staying one week in Bangalore for his work.

A case of sycotic miasm:

     Patient aged 42 yrs. Professionally lecturer. He was suffering from Asthma since 19 yrs. Asthmatic attacks < night 2.30 A.M. winter, > by sifting, leaning forward on the table and warmth. After giving Kali carb 1m, raised to 10m then in infrequent doses for 4 months, the patient is now perfectly all right. There is no asthmatic attack.

A case of syphilitic miasm:

     This is a case of syphilitic miasm, patient aged 42 yrs, suffering from frequent attacks of Aphthae in mouth since 2 yrs. He is a rice merchant. Due to untimely meals, he has this complaint. After psorinum 1m one dose, followed with merc sol 1m in frequent doses for 6 months. Now the patient is not having any aphthae in his mouth.