Hahnemann completed the 6th edition of Organon
in 1842 while in active practice in Paris, but the same did not see
the light of the day till 1921 long after his death in 1843 for various
unavoidable reasons. He made many changes in the 6th edition, until
but the most important of them are regarding the preparation of homoeopathic
medicines in their mother form and subsequent potencies and also their
administration in patients.
These valuable changes passed unnoticed for some time and were lying
as the hidden treasure of the 6th edition serious studies and diligence
of some stalwarts of homoeopathic profession brought it out. But these
changes didn’t come all on a sudden; they evolved slowly in course
of several years of experiment and observation out of dire necessity.
Even then many advantages are experienced over usefulness of LM potency
we should remember some disadvantages too.

Disadvantages
Medicines must be administered in liquid form so to prevent
the decomposition of water and rectified spirit.
Standard quality of phial and cork are essential to preserve
the medicinal solution for long time.
Repeated administration of a partially indicated medicine
may give relief on the chief complaints of the patients but the patient
as a whole does not improve as the medicine dose does not cover the fundamental
cause and the totality of symptoms.
In simple and uncomplicated chronic disease of dynamic
pathology it is easier to observe the effect of the medicine by administering
a single dose of centesimal potency. But this is not possible with the
medicine of 50- millesimal scale of potency.
The intricacy of the mode of use of the medicine and regulation
of the so-called aggravation, though very mild lead to lack of enthusiasm
amongst many of us.
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